TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING

Uncontrolled immune responses to intracellular DNA have been shown to induce autoimmune diseases. Homeostasis regulation of immune responses to cytosolic DNA is critical for limiting the risk of autoimmunity and survival of the host. Here, we report that the E3 ubiquitin ligase tripartite motif prot...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Wang, Yanming, Lian, Qiaoshi, Yang, Bo, Yan, Shanshan, Zhou, Haiyan, He, Lan, Lin, Guomei, Lian, Zhexiong, Jiang, Zhengfan, Sun, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482643/
https://ncbi.nlm.nih.gov/pubmed/26114947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005012
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