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Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase

The human methyltransferases (MTases) METTL21A and VCP-KMT (METTL21D) were recently shown to methylate single lysine residues in Hsp70 proteins and in VCP, respectively. The yet uncharacterized MTase encoded by the YNL024C gene in Saccharomyces cerevisiae shows high sequence similarity to METTL21A a...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jakobsson, Magnus E., Davydova, Erna, Małecki, Jędrzej, Moen, Anders, Falnes, Pål Ø.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482628/
https://ncbi.nlm.nih.gov/pubmed/26115316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131426
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