The Effect of Nrf2 Pathway Activation on Human Pancreatic Islet Cells

BACKGROUND: Pancreatic islets are known to contain low level of antioxidants that renders them vulnerable to oxidative stress. Nrf2 is the master regulator of numerous genes, encoding antioxidant, detoxifying, and cytoprotective molecules. Activation of Nrf2 pathway induces up-regulation of numerous...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Masuda, Yuichi, Vaziri, Nosratola D., Li, Shiri, Le, Aimee, Hajighasemi-Ossareh, Mohammad, Robles, Lourdes, Foster, Clarence E., Stamos, Michael J., Al-Abodullah, Ismail, Ricordi, Camillo, Ichii, Hirohito
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482439/
https://ncbi.nlm.nih.gov/pubmed/26110640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131012
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