The Effect of Nrf2 Pathway Activation on Human Pancreatic Islet Cells

BACKGROUND: Pancreatic islets are known to contain low level of antioxidants that renders them vulnerable to oxidative stress. Nrf2 is the master regulator of numerous genes, encoding antioxidant, detoxifying, and cytoprotective molecules. Activation of Nrf2 pathway induces up-regulation of numerous...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Masuda, Yuichi, Vaziri, Nosratola D., Li, Shiri, Le, Aimee, Hajighasemi-Ossareh, Mohammad, Robles, Lourdes, Foster, Clarence E., Stamos, Michael J., Al-Abodullah, Ismail, Ricordi, Camillo, Ichii, Hirohito
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482439/
https://ncbi.nlm.nih.gov/pubmed/26110640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131012
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