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The Effect of Nrf2 Pathway Activation on Human Pancreatic Islet Cells

BACKGROUND: Pancreatic islets are known to contain low level of antioxidants that renders them vulnerable to oxidative stress. Nrf2 is the master regulator of numerous genes, encoding antioxidant, detoxifying, and cytoprotective molecules. Activation of Nrf2 pathway induces up-regulation of numerous...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Masuda, Yuichi, Vaziri, Nosratola D., Li, Shiri, Le, Aimee, Hajighasemi-Ossareh, Mohammad, Robles, Lourdes, Foster, Clarence E., Stamos, Michael J., Al-Abodullah, Ismail, Ricordi, Camillo, Ichii, Hirohito
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482439/
https://ncbi.nlm.nih.gov/pubmed/26110640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131012
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