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Catalytic and Biocatalytic Iron Porphyrin Carbene Formation: Effects of Binding Mode, Carbene Substituent, Porphyrin Substituent, and Protein Axial Ligand

[Image: see text] Iron porphyrin carbenes (IPCs) are important intermediates in various chemical reactions catalyzed by iron porphyrins and engineered heme proteins, as well as in the metabolism of various xenobiotics by cytochrome P450. However, there are no prior theoretical reports to help unders...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Khade, Rahul L., Zhang, Yong
Format: Artigo
Language:Inglês
Published: American Chemical Society 2015
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482416/
https://ncbi.nlm.nih.gov/pubmed/26067900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03437
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