Adipose cells promote resistance of breast cancer cells to trastuzumab-mediated antibody-dependent cellular cytotoxicity

INTRODUCTION: Trastuzumab has been used in the treatment of human epidermal growth factor receptor 2 (HER2)-expressing breast cancer, but its efficacy is limited by de novo or acquired resistance. Although many mechanisms have been proposed to explain resistance to trastuzumab, little is known conce...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Main Authors: Duong, Minh Ngoc, Cleret, Aurore, Matera, Eva-Laure, Chettab, Kamel, Mathé, Doriane, Valsesia-Wittmann, Sandrine, Clémenceau, Béatrice, Dumontet, Charles
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482271/
https://ncbi.nlm.nih.gov/pubmed/25908175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0569-0
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