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Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway
Trastuzumab-emtansine (T-DM1) is an antibody-drug conjugate that specifically targets HER2 thanks to its antibody component trastuzumab. In spite of responses to this novel agent, acquired resistance to treatment remains a major obstacle. Prolonged in vitro exposure of the gastroesophageal junction...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940380/ https://ncbi.nlm.nih.gov/pubmed/29765526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24975 |
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