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Effect of kinase inhibitors on the therapeutic properties of monoclonal antibodies

Targeted therapies of malignancies currently consist of therapeutic monoclonal antibodies and small molecule kinase inhibitors. The combination of these novel agents raises the issue of potential antagonisms. We evaluated the potential effect of 4 kinase inhibitors, including the Bruton tyrosine kin...

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Библиографические подробности
Опубликовано в: :MAbs
Главные авторы: Duong, Minh Ngoc, Matera, Eva-Laure, Mathé, Doriane, Evesque, Anne, Valsesia-Wittmann, Sandrine, Clémenceau, Béatrice, Dumontet, Charles
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622495/
https://ncbi.nlm.nih.gov/pubmed/25523586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2015.989020
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