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Effect of kinase inhibitors on the therapeutic properties of monoclonal antibodies

Targeted therapies of malignancies currently consist of therapeutic monoclonal antibodies and small molecule kinase inhibitors. The combination of these novel agents raises the issue of potential antagonisms. We evaluated the potential effect of 4 kinase inhibitors, including the Bruton tyrosine kin...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Duong, Minh Ngoc, Matera, Eva-Laure, Mathé, Doriane, Evesque, Anne, Valsesia-Wittmann, Sandrine, Clémenceau, Béatrice, Dumontet, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622495/
https://ncbi.nlm.nih.gov/pubmed/25523586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2015.989020
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