CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells

We report anticarcinogenic effects of suicide gene therapy that relies on the use of resveratrol-responsive CArG elements from the Egr-1 promoter to induce GADD45α. In A549 lung cancer cells, endogenous GADD45α was not induced upon resveratrol treatment. Therefore, induction of exogenous GADD45α res...

Full description

Saved in:
Bibliographic Details
Published in:Genes Cancer
Main Authors: Shi, Qiwen, Geldenhuys, Werner, Sutariya, Vijaykumar, Bishayee, Anupam, Patel, Isha, Bhatia, Deepak
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482243/
https://ncbi.nlm.nih.gov/pubmed/26124921
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items