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Sequential activation of Elk-1/Egr-1/GADD45α by arsenic

Long-term exposure to arsenic, an environmental contaminant, leads to increased risks of cancers. In the present study, we investigated the sequential regulation of Elk-1 and Egr-1 on As(3+)-induced GADD45α, an effector of G2/M checkpoint. We found that As3+ transcriptionally induced both Elk-1 and...

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Detalhes bibliográficos
Main Authors: Shi, Qiwen, Sutariya, Vijaykumar, Bishayee, Anupam, Bhatia, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116526/
https://ncbi.nlm.nih.gov/pubmed/25004251
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