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Characterization of an alternatively spliced GADD45α, GADD45α1 isoform, in arsenic-treated epithelial cells

A new GADD45α isoform, GADD45α1, was identified in the cellular response to arsenic. DNA sequencing and biochemical analyses suggested that GADD45α1 is derived from an alternative splicing of the GADD45α mRNA by skipping the region corresponding to exon2 of the gadd45α gene during mRNA maturation. I...

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Bibliographic Details
Main Authors: Zhang, Yadong, Beezhold, Kevin, Castranova, Vince, Shi, Xianglin, Chen, Fei
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680285/
https://ncbi.nlm.nih.gov/pubmed/18942077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20483
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