Salivary Thromboxane A2-Binding Proteins from Triatomine Vectors of Chagas Disease Inhibit Platelet-Mediated Neutrophil Extracellular Traps (NETs) Formation and Arterial Thrombosis

BACKGROUND: The saliva of blood-feeding arthropods contains a notable diversity of molecules that target the hemostatic and immune systems of the host. Dipetalodipin and triplatin are triatomine salivary proteins that exhibit high affinity binding to prostanoids, such as TXA2, thus resulting in pote...

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Detaylı Bibliyografya
Yayımlandı:PLoS Negl Trop Dis
Asıl Yazarlar: Mizurini, Daniella M., Aslan, Jorgeane S., Gomes, Tainá, Ma, Dongying, Francischetti, Ivo M. B., Monteiro, Robson Q.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482233/
https://ncbi.nlm.nih.gov/pubmed/26110417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003869
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