Salivary Thromboxane A2-Binding Proteins from Triatomine Vectors of Chagas Disease Inhibit Platelet-Mediated Neutrophil Extracellular Traps (NETs) Formation and Arterial Thrombosis

BACKGROUND: The saliva of blood-feeding arthropods contains a notable diversity of molecules that target the hemostatic and immune systems of the host. Dipetalodipin and triplatin are triatomine salivary proteins that exhibit high affinity binding to prostanoids, such as TXA2, thus resulting in pote...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Mizurini, Daniella M., Aslan, Jorgeane S., Gomes, Tainá, Ma, Dongying, Francischetti, Ivo M. B., Monteiro, Robson Q.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482233/
https://ncbi.nlm.nih.gov/pubmed/26110417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003869
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