A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin

LiaR is a ‘master regulator’ of the cell envelope stress response in enterococci and many other Gram-positive organisms. Mutations to liaR can lead to antibiotic resistance to a variety of antibiotics including the cyclic lipopeptide daptomycin. LiaR is phosphorylated in response to membrane stress...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Davlieva, Milya, Shi, Yiwen, Leonard, Paul G., Johnson, Troy A., Zianni, Michael R., Arias, Cesar A., Ladbury, John E., Shamoo, Yousif
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Structural Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482077/
https://ncbi.nlm.nih.gov/pubmed/25897118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv321
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