A trimming-and-retrieving alignment scheme for reduced representation bisulfite sequencing

Summary: Currently available bisulfite sequencing tools frequently suffer from low mapping rates and low methylation calls, especially for data generated from the Illumina sequencer, NextSeq. Here, we introduce a sequential trimming-and-retrieving alignment approach for investigating DNA methylation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Wang, Xuefeng, Yu, Xiaoqing, Zhu, Wei, McCombie, W. Richard, Antoniou, Eric, Powers, R. Scott, Davidson, Nicholas O., Li, Ellen, Williams, Jennie
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Applications Notes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481698/
https://ncbi.nlm.nih.gov/pubmed/25681254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv089
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