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Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease.

Neuropathological findings in three aged chimpanzees were compared with those in rhesus monkeys and individuals with Alzheimer disease. Senile plaques and blood vessels were immunoreactive for amyloid beta-protein and apolipoprotein E (apoE) in the nonhuman primates, recapitulating findings in human...

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Detalhes bibliográficos
Main Authors: Gearing, M, Rebeck, G W, Hyman, B T, Tigges, J, Mirra, S S
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44816/
https://ncbi.nlm.nih.gov/pubmed/7937774
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