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Cerebrovascular Effects of Apolipoprotein E: Implications for Alzheimer’s disease

Human apolipoprotein (apo) E has three isoforms: apoE2, apoE3 and apoE4. APOE4 is a major genetic risk factor for Alzheimer’s disease (AD), and is associated with dementia in Down’s syndrome and poor neurological outcome after traumatic brain injury, cerebral hemorrhage and other neuropathological d...

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Detalles Bibliográficos
Publicado en:JAMA Neurol
Autor Principal: Zlokovic, Berislav V.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414030/
https://ncbi.nlm.nih.gov/pubmed/23400708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.2152
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