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The E3 ubiquitin ligase TRIM32 regulates myoblast proliferation by controlling turnover of NDRG2

Limb girdle muscular dystrophy 2H is caused by mutations in the gene encoding the E3 ubiquitin ligase, TRIM32. Previously, we generated and characterized a Trim32 knockout mouse (T32KO) that displays both neurogenic and myopathic features. The myopathy in these mice is attributable to impaired muscl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Mokhonova, Ekaterina I., Avliyakulov, Nuraly K., Kramerova, Irina, Kudryashova, Elena, Haykinson, Michael J., Spencer, Melissa J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481581/
https://ncbi.nlm.nih.gov/pubmed/25701873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv049
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