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Lafora disease E3-ubiquitin ligase malin is related to TRIM32 at both the phylogenetic and functional level

BACKGROUND: Malin is an E3-ubiquitin ligase that is mutated in Lafora disease, a fatal form of progressive myoclonus epilepsy. In order to perform its function, malin forms a functional complex with laforin, a glucan phosphatase that facilitates targeting of malin to its corresponding substrates. Wh...

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Main Authors: Romá-Mateo, Carlos, Moreno, Daniel, Vernia, Santiago, Rubio, Teresa, Bridges, Travis M, Gentry, Matthew S, Sanz, Pascual
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160408/
https://ncbi.nlm.nih.gov/pubmed/21798009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-225
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