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Lafora disease E3-ubiquitin ligase malin is related to TRIM32 at both the phylogenetic and functional level
BACKGROUND: Malin is an E3-ubiquitin ligase that is mutated in Lafora disease, a fatal form of progressive myoclonus epilepsy. In order to perform its function, malin forms a functional complex with laforin, a glucan phosphatase that facilitates targeting of malin to its corresponding substrates. Wh...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160408/ https://ncbi.nlm.nih.gov/pubmed/21798009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-225 |
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