A major role of insulin in promoting obesity-associated adipose tissue inflammation

OBJECTIVE: Adipose tissue (AT) inflammation is associated with systemic insulin resistance and hyperinsulinemia in obese rodents and humans. A longstanding concept is that hyperinsulinemia may promote systemic insulin resistance through downregulation of its receptor on target tissues. Here we teste...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Pedersen, David J., Guilherme, Adilson, Danai, Laura V., Heyda, Lauren, Matevossian, Anouch, Cohen, Jessica, Nicoloro, Sarah M., Straubhaar, Juerg, Noh, Hye Lim, Jung, DaeYoung, Kim, Jason K., Czech, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481426/
https://ncbi.nlm.nih.gov/pubmed/26137438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.04.003
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