Regulatory CD8(+)CD122(+) T-cells predominate in CNS after treatment of experimental stroke in male mice with IL-10-secreting B-cells

Clinical stroke induces inflammatory processes leading to cerebral and splenic injury and profound peripheral immunosuppression. IL-10 expression is elevated during major CNS diseases and limits inflammation in the brain. Recent evidence demonstrated that transfer of IL-10(+) B-cells reduced infarct...

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Bibliographic Details
Published in:Metab Brain Dis
Main Authors: Bodhankar, Sheetal, Chen, Yingxin, Lapato, Andrew, Vandenbark, Arthur A., Murphy, Stephanie J., Saugstad, Julie A., Offner, Halina
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481189/
https://ncbi.nlm.nih.gov/pubmed/25537181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-014-9639-8
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