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Production of extrachromosomal microDNAs is linked to mismatch repair pathways and transcriptional activity

MicroDNAs are <400-base extrachromosomal circles found in mammalian cells. Tens of thousands of microDNAs have been found in all tissue types, including sperm. MicroDNAs arise preferentially from areas with high gene density, GC content, and exon density, from promoters with activating chromatin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Dillon, Laura W., Kumar, Pankaj, Shibata, Yoshiyuki, Wang, Yuh-Hwa, Willcox, Smaranda, Griffith, Jack D., Pommier, Yves, Takeda, Shunichi, Dutta, Anindya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481157/
https://ncbi.nlm.nih.gov/pubmed/26051933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.020
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