Oncogenic mutations of thyroid hormone receptor β

The C-terminal frame-shift mutant of the thyroid hormone receptor TRβ1, PV, functions as an oncogene. An important question is whether the oncogenic activity of mutated TRβ1 is uniquely dependent on the PV mutated sequence. Using four C-terminal frame-shift mutants—PV, Mkar, Mdbs, and AM—we examined...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Park, Jeong Won, Zhao, Li, Willingham, Mark, Cheng, Sheue-yann
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480739/
https://ncbi.nlm.nih.gov/pubmed/25924236
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