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Arterial Spin-Labeled Perfusion Combined with Segmentation Techniques to Evaluate Cerebral Blood Flow in White and Gray Matter of Children with Sickle Cell Anemia

BACKGROUND: Changes in cerebral perfusion are an important feature of the pathophysiology of sickle cell anemia (SCA); cerebrovascular ischemia occurs frequently and leads to neurocognitive deficits, silent infarcts, and overt stroke. Non-invasive MRI methods to measure cerebral blood flow (CBF) by...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Helton, Kathleen J., Paydar, Amir, Glass, John, Weirich, Eric M., Hankins, Jane, Li, Chin-Shang, Smeltzer, Matthew P., Wang, Winfred C., Ware, Russell E., Ogg, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480678/
https://ncbi.nlm.nih.gov/pubmed/18937311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.21745
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