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Aging Results in Differential Regulation of DNA Repair Pathways in Pachytene Spermatocytes in the Brown Norway Rat

The present trend of increasing paternal age is accompanied by concerns for the development of complex multigene diseases (e.g., autism and schizophrenia) in progeny. Recent studies have established strong correlations between male age, increased oxidative stress, decreased sperm quality, and struct...

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Bibliografiske detaljer
Udgivet i:Biol Reprod
Main Authors: Paul, Catriona, Nagano, Makoto, Robaire, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: Society for the Study of Reproduction, Inc. 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480431/
https://ncbi.nlm.nih.gov/pubmed/21865553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.094219
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