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Differential Age-Associated Regulation of Clusterin Expression in Prostate Lobes of Brown Norway Rats

BACKGROUND: Serum androgen concentrations decline with age in male Brown Norway rats and castration induces apoptosis of luminal secretory epithelial cells in the ventral but not in the dorsal and lateral prostate lobes. Clusterin has been described as an androgen-repressed gene and a protein with e...

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Détails bibliographiques
Auteurs principaux: Omwancha, Josephat, Anway, Matthew D., Brown, Terry R.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612093/
https://ncbi.nlm.nih.gov/pubmed/18942093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20866
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