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Aging Results in Differential Regulation of DNA Repair Pathways in Pachytene Spermatocytes in the Brown Norway Rat

The present trend of increasing paternal age is accompanied by concerns for the development of complex multigene diseases (e.g., autism and schizophrenia) in progeny. Recent studies have established strong correlations between male age, increased oxidative stress, decreased sperm quality, and struct...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Paul, Catriona, Nagano, Makoto, Robaire, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480431/
https://ncbi.nlm.nih.gov/pubmed/21865553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.094219
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