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Monophosphoryl lipid A inhibits the cytokine response of endothelial cells challenged with LPS
Monophosphoryl lipid A (MPLA) is a TLR4 agonist that is used as an immunomodulator in human vaccines; additionally, it has been shown to be protective in models of sepsis. As endothelial cells regulate inflammation, we hypothesized that MPLA would decrease activation of human umbilical vein endothel...
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| Publicado no: | Innate Immun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480205/ https://ncbi.nlm.nih.gov/pubmed/25540284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425914564172 |
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