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mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging
The mechanistic target of rapamycin (mTOR) is a ubiquitous serine/threonine kinase that plays pivotal roles in integrating growth signals on a cellular level. To support proliferation and survival under stress, two interacting complexes that harbor mTOR, mTORC1 and mTORC2, promote the transcription...
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| Udgivet i: | Ann N Y Acad Sci |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480196/ https://ncbi.nlm.nih.gov/pubmed/25907074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12756 |
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