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mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

The mechanistic target of rapamycin (mTOR) is a ubiquitous serine/threonine kinase that plays pivotal roles in integrating growth signals on a cellular level. To support proliferation and survival under stress, two interacting complexes that harbor mTOR, mTORC1 and mTORC2, promote the transcription...

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Detalhes bibliográficos
Publicado no:Ann N Y Acad Sci
Autor principal: Perl, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480196/
https://ncbi.nlm.nih.gov/pubmed/25907074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12756
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