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A simple method for generating high-resolution maps of genome-wide protein binding

Chromatin immunoprecipitation (ChIP) and its derivatives are the main techniques used to determine transcription factor binding sites. However, conventional ChIP with sequencing (ChIP-seq) has problems with poor resolution, and newer techniques require significant experimental alterations and comple...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Skene, Peter J, Henikoff, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480131/
https://ncbi.nlm.nih.gov/pubmed/26079792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09225
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