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High-Resolution Genome-Wide Mapping of Transposon Integration in Mammals

The Sleeping Beauty (SB) transposon is an emerging tool for transgenesis, gene discovery, and therapeutic gene delivery in mammals. Here we studied 1,336 SB insertions in primary and cultured mammalian cells in order to better understand its target site preferences. We report that, although widely d...

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Detalhes bibliográficos
Main Authors: Yant, Stephen R., Wu, Xiaolin, Huang, Yong, Garrison, Brian, Burgess, Shawn M., Kay, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061620/
https://ncbi.nlm.nih.gov/pubmed/15743807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2085-2094.2005
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