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High-Resolution Genome-Wide Mapping of Transposon Integration in Mammals

The Sleeping Beauty (SB) transposon is an emerging tool for transgenesis, gene discovery, and therapeutic gene delivery in mammals. Here we studied 1,336 SB insertions in primary and cultured mammalian cells in order to better understand its target site preferences. We report that, although widely d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yant, Stephen R., Wu, Xiaolin, Huang, Yong, Garrison, Brian, Burgess, Shawn M., Kay, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061620/
https://ncbi.nlm.nih.gov/pubmed/15743807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2085-2094.2005
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