High-Resolution Genome-Wide Mapping of Transposon Integration in Mammals

The Sleeping Beauty (SB) transposon is an emerging tool for transgenesis, gene discovery, and therapeutic gene delivery in mammals. Here we studied 1,336 SB insertions in primary and cultured mammalian cells in order to better understand its target site preferences. We report that, although widely d...

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Bibliographic Details
Main Authors: Yant, Stephen R., Wu, Xiaolin, Huang, Yong, Garrison, Brian, Burgess, Shawn M., Kay, Mark A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061620/
https://ncbi.nlm.nih.gov/pubmed/15743807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2085-2094.2005
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