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Topological data analysis generates high-resolution, genome-wide maps of human recombination

Meiotic recombination is a fundamental evolutionary process driving diversity in eukaryotes. In mammals, recombination is known to occur preferentially at specific genomic regions. Using topological data analysis (TDA), a branch of applied topology that extracts global features from large datasets,...

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Bibliographic Details
Published in:Cell Syst
Main Authors: Camara, Pablo G., Rosenbloom, Daniel I. S., Emmett, Kevin J., Levine, Arnold J., Rabadan, Raul
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965322/
https://ncbi.nlm.nih.gov/pubmed/27345159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.05.008
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