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An Alternative Phosphorylation Switch in Integrin β2 (CD18) Tail for Dok1 Binding

Integrins are involved in cell migration and adhesion. A large number of proteins interact with the cytoplasmic tails of integrins. Dok1 is a negative regulator of integrin activation and it binds to the phosphorylated membrane proximal NxxY motif in a number of integrin β tails. The β tail of the β...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Gupta, Sebanti, Chit, Joel Chia-Yeong, Feng, Chen, Bhunia, Anirban, Tan, Suet-Mien, Bhattacharjya, Surajit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479986/
https://ncbi.nlm.nih.gov/pubmed/26108885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11630
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