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An Alternative Phosphorylation Switch in Integrin β2 (CD18) Tail for Dok1 Binding
Integrins are involved in cell migration and adhesion. A large number of proteins interact with the cytoplasmic tails of integrins. Dok1 is a negative regulator of integrin activation and it binds to the phosphorylated membrane proximal NxxY motif in a number of integrin β tails. The β tail of the β...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479986/ https://ncbi.nlm.nih.gov/pubmed/26108885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11630 |
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