Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro

Osteoclasts reside on bone and are the main bone resorbing cells playing an important role in bone homeostasis, while natural killer (NK) cells are bone-marrow-derived cells known to play a crucial role in immune defence against viral infections. Although mature NK cells traffic through bone marrow...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Feng, Shan, Madsen, Suzi H, Viller, Natasja N, Neutzsky-Wulff, Anita V, Geisler, Carsten, Karlsson, Lars, Söderström, Kalle
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479536/
https://ncbi.nlm.nih.gov/pubmed/25684021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12449
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