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In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists
The orphan nuclear receptor, retinoic acid receptor-related orphan nuclear receptor γt (RORγt), is required for the development and pathogenic function of interleukin-17A-secreting CD4(+) T helper type 17 (Th17) cells. Whereas small molecule RORγt antagonists impair Th17 cell development and attenua...
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| 出版年: | Immunology |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley & Sons, Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479534/ https://ncbi.nlm.nih.gov/pubmed/25604624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12444 |
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