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Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice

Diabetes mellitus-associated damage to the microvasculature of the brain is caused by hyperglycemia-induced oxidative stress, which results in pericyte loss, blood-brain barrier disruption, and impaired cognitive function. Oxidative stress, in diabetes, is caused by reactive oxygen species produced...

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Publicat a:Int Libr Diabetes Metab
Autors principals: Price, Tulin O., Farr, Susan A., Niehoff, Michael L., Ercal, Nuran, Morley, John E., Shah, Gul N.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479302/
https://ncbi.nlm.nih.gov/pubmed/26120599
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