Conformational effects of environmentally induced, cancer-related mutations in the p53 protein.

The tumor suppressor gene p53 has been identified as the most frequent target of genetic alterations in human cancers. A considerable number of environmentally induced, cancer-related p53 mutations in human tumors have been found in a highly conserved proline-rich sequence of the p53 protein encompa...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Brandt-Rauf, P W, Monaco, R, Pincus, M R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9262
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