Conformational effects of environmentally induced, cancer-related mutations in the p53 protein.
The tumor suppressor gene p53 has been identified as the most frequent target of genetic alterations in human cancers. A considerable number of environmentally induced, cancer-related p53 mutations in human tumors have been found in a highly conserved proline-rich sequence of the p53 protein encompa...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1994
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9262 |
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