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Conformational effects of environmentally induced, cancer-related mutations in the p53 protein.

The tumor suppressor gene p53 has been identified as the most frequent target of genetic alterations in human cancers. A considerable number of environmentally induced, cancer-related p53 mutations in human tumors have been found in a highly conserved proline-rich sequence of the p53 protein encompa...

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Bibliografiska uppgifter
Huvudupphovsmän: Brandt-Rauf, P W, Monaco, R, Pincus, M R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC44792/
https://ncbi.nlm.nih.gov/pubmed/7937752
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