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Ferroportin deficiency impairs manganese metabolism in flatiron mice
We examined the physiologic role of ferroportin (Fpn) in manganese (Mn) export using flatiron (ffe/+) mice, a genetic model of Fpn deficiency. Blood (0.0123 vs. 0.0107 mg/kg; P = 0.0003), hepatic (1.06 vs. 0.96 mg/kg; P = 0.0125), and bile Mn levels (79 vs. 38 mg/kg; P = 0.0204) were reduced in ffe/...
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| Izdano u: | FASEB J |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Federation of American Societies for Experimental Biology
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478796/ https://ncbi.nlm.nih.gov/pubmed/25782988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-262592 |
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