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Ferroportin disease mutations influence manganese accumulation and cytotoxicity

Hemochromatosis is a frequent genetic disorder, characterized by the accumulation of excess iron across tissues. Mutations in the FPN1 gene, encoding a cell surface iron exporter [ferroportin (Fpn)], are responsible for hemochromatosis type 4, also known as ferroportin disease. Recently, Fpn has bee...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Choi, Eun-Kyung, Nguyen, Trang-Tiffany, Iwase, Shigeki, Seo, Young Ah
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338638/
https://ncbi.nlm.nih.gov/pubmed/30247984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800831R
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