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EnD-Seq and AppEnD: sequencing 3′ ends to identify nontemplated tails and degradation intermediates
Existing methods for detecting RNA intermediates resulting from exonuclease degradation are low-throughput and laborious. In addition, mapping the 3′ ends of RNA molecules to the genome after high-throughput sequencing is challenging, particularly if the 3′ ends contain post-transcriptional modifica...
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Publicado no: | RNA |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478355/ https://ncbi.nlm.nih.gov/pubmed/26015596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048785.114 |
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