The Drosophila U7 snRNP proteins Lsm10 and Lsm11 are required for histone pre-mRNA processing and play an essential role in development

Metazoan replication-dependent histone mRNAs are not polyadenylated, and instead terminate in a conserved stem–loop structure generated by an endonucleolytic cleavage of the pre-mRNA involving U7 snRNP. U7 snRNP contains two like-Sm proteins, Lsm10 and Lsm11, which replace SmD1 and SmD2 in the canon...

Full description

Saved in:
Bibliographic Details
Main Authors: Godfrey, Ashley C., White, Anne E., Tatomer, Deirdre C., Marzluff, William F., Duronio, Robert J.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743060/
https://ncbi.nlm.nih.gov/pubmed/19620235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1518009
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items