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The Drosophila U7 snRNP proteins Lsm10 and Lsm11 are required for histone pre-mRNA processing and play an essential role in development

Metazoan replication-dependent histone mRNAs are not polyadenylated, and instead terminate in a conserved stem–loop structure generated by an endonucleolytic cleavage of the pre-mRNA involving U7 snRNP. U7 snRNP contains two like-Sm proteins, Lsm10 and Lsm11, which replace SmD1 and SmD2 in the canon...

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Detalhes bibliográficos
Main Authors: Godfrey, Ashley C., White, Anne E., Tatomer, Deirdre C., Marzluff, William F., Duronio, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743060/
https://ncbi.nlm.nih.gov/pubmed/19620235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1518009
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