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Lipophilic prodrug conjugates allow facile and rapid synthesis of high loading capacity liposomes without the need for post-assembly purification

Dihydropyridopyrazoles are simplified synthetic analogues of podophyllotoxin that can effectively mimic its molecular scaffold and act as potent mitotic spindle poisons in dividing cancer cells. However, despite nanomolar potencies and ease of synthetic preparation, further clinical development of t...

詳細記述

保存先:
書誌詳細
出版年:J Liposome Res
主要な著者: Mikhalin, Alexander A., Evdokimov, Nikolai M., Frolova, Liliya V., Magedov, Igor V., Kornienko, Alexander, Johnston, Robert, Rogelj, Snezna, Tartis, Michaelann S.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478286/
https://ncbi.nlm.nih.gov/pubmed/25534989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08982104.2014.992022
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