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Phospholipid prodrug conjugates of insoluble chemotherapeutic agents for ultrasound targeted drug delivery

The hydrophobicity and high potency of many therapeutic agents makes them difficult to use effectively in clinical practice. This work focuses on conjugating phospholipid tails (2T) onto podophyllotoxin (P) and its analogue (N) using a linker and characterizing the effects of their incorporation int...

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Bibliographic Details
Published in:Nanotheranostics
Main Authors: Márquez, Mendi G., Dotson, Rachel, Pias, Sally, Frolova, Liliya V., Tartis, Michaelann S.
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940203/
https://ncbi.nlm.nih.gov/pubmed/31911893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ntno.37738
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